High Throughput Experimentation CELLEX-ICIQ Laboratory
THE UNIT IN 2017
The High Throughput Experimentation (HTE) laboratory is a facility that makes accessible to all ICIQ researchers the instrumentation and know-how to run a large number of reactions at micro-scale and analyze them in a short period of time.
The facility is prepared to run different kinds of reactions in 24 or 96 well plates, including those that are air sensitive, reactions with reactive gases, photochemical reactions or reactions under pressure conditions. Moreover, the Laboratory is stocked with a large number of reagents, solvents, metals and ligands to run the reactions. All together, the library is formed by almost 800 compounds.
Regarding the analysis of the reactions, the lab is equipped with an NMR spectrometer and three chromatographs: a GC-MS-FID, a UHPLC-MS and a supercritical CO2 chromatograph with diode array or MS detector.
In 2017 a new photoreactor to work with reactive gas was developed and built in house. Moreover, new 24 and 96 position reactors with minimal dead volume to work under pressure (20 bar) were set up.
During 2017, 172 experiments were run, with an average of 72 reactions per experiment. This means that around 12400 reactions were run and analysed in the HTE Unit in 2017. In 2017, the number of reactions run in the lab decreased by 13%, but the number of average reactions per experiment increased from 53 in 2016 to 72 in 2017.